[发明专利]用于治疗疼痛的氘代化合物

摘要

本发明提供对于治疗疼痛或其相关疾病或病症有用的新型化合物，和其药物组合物及制备方法和用途。

主权项

1.一种化合物或其药学上可接受的形式，所述化合物具有以下结构式：其中R₁、R₂、R₃、R₄、R₅、R₆、R_6’、R₇、R_7’、R₈、R_8’、R₉、R₁₀、R₁₁、R₁₂、R₁₃、R_13’、R₁₄、R_14’、R₁₅、R_15’、R₁₆、R_16’、R₁₇、R_17’、R₁₈、R_18’、R₁₉和R_19’各自独立地选自H和D，并且R₄、R₅、R₆、R_6’、R₇、R_7’、R₈、R_8’、R₉、R₁₀、R₁₁、R₁₂、R₁₃、R_13’、R₁₄、R_14’、R₁₅、R_15’、R₁₆、R_16’、R₁₇、R_17’、R₁₈、R_18’、R₁₉和R_19’中的至少一个为D。